IRON, FERRITIN, HEREDITARY FERRITINOPATHY, AND NEURODEGENERATION

Iron, Ferritin, Hereditary Ferritinopathy, and Neurodegeneration

Cellular growth, function, and protection require proper iron management, and ferritin plays a crucial role as the major iron sequestration and storage protein.Ferritin is a 24 subunit spherical shell protein composed of both light (FTL) and heavy chain (FTH1) subunits, possessing complimentary iron-handling functions and forming three-fold and fou

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Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

"nBackground: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy Cables leading to the loss of central vision.  The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secon­dary genetic and/or epigenetic risk factors are suggested to influence its n

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W Band Imaging System Using Linear Sparse Periodic Antenna Array and Compressive Sensing for Personnel Screening

This paper presents our study on a W band imaging system consisting of a linear sparse periodic antenna array (SPA) with only 10 transmitting (Tx) and 10 receiving (Rx) elements in simulation and experiment for the purpose of personnel screening.We have devised a simplified and low cost experimental set-up using only 1 Tx and 1 Rx Kitchenwares chan

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Polymorphisms within the TNFSF4 and MAPKAPK2 Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium

Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA).We conducted a two-stage case control study including 911 high-risk patients diagnosed with hematological malignancies that were ascertained through the aspBIOmics consortium.The meta-a

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